My research and education focus is on cardiovascular structure and function.
Specific topics include arterial wall biomechanics and adaptation, and ventricular-vascular interaction.
My approach is to merge the disciplines and tools of engineering and clinical sciences to develop improved assessment methods to better understand degenerative and adaptive processes.
Examples of future graduate student projects:
A processing pipeline to estimate the force-length relation of a fiber network - effect of structural damage
Consitutive model extension to account for smooth muscle tone - how to modulate vessel stiffness?
Establishing the reliability of axial stretch setting in biaxial mechanical testing of mouse arteries - how precise do we need to be?
Effect of the cold pressor test on carotid artery distensibility - can we learn more from modulated vessel stiffness?
Extraction of cardiac timing intervals from carotid distension waveforms - a window on the heart
Changes in left ventricular relaxation due to an acute decrease in arterial compliance - data from pigs
MSc in Electrical Engineering, PhD in Biomedical Engineering
Vascular Structure & Function, Hemodynamics, Ultrasound, Signal Processing, Control Systems Theory, Biomedical Instrumentation, Electronics